6-Methoxyhexan-1-ol → 6-Methoxyhexanoic acid

HRID 964770Notes

Reaction equation

HRID 964770 reaction equation

[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][OH:9].CC(C)=[O:12].OS(O)(=O)=O.O=[Cr](=O)=O>CC(C)=O>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]([OH:12])=[O:9]

Participants

4

Reactant 2

HCID 126516996-Methoxyhexan-1-ol

HCID 131709961Jones' reagent

Product 1

HCID 150030106-Methoxyhexanoic acid

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

6-Methoxy-hexanol (8.16 g) was oxidized with Jones reagent (2.67-M, 53 ml) in acetone (100 ml) at -10° C. to give 6.17 g of 6-methoxy-caproic acid.

Sources & evidence

ORD record: ord-138129e15e2242ae8e02aca2236de03e
Source dataset: uspto-grants-1998_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05770759

Reaction notes

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