Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9648Generated: October 25, 2026

4-(Trifluoromethyl)phenol → {3-{[4-(Trifluoromethyl)phenoxy]methyl}-5-[4-(trifluoromethyl)phenyl]thien-2-yl}methanol

https://huagongshe.com/reaction/9648

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)phenolHCID 67874—
ReactantEthyl 3-(bromomethyl)-5-[4-(trifluoromethyl)phenyl]thiophene-2-carboxylateHCID 21986402—
Product{3-{[4-(Trifluoromethyl)phenoxy]methyl}-5-[4-(trifluoromethyl)phenyl]thien-2-yl}methanolHCID 21986459—

Reaction Steps

Prepared from intermediate 43 and 4-(trifluoromethyl)phenol

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091237B2
Source datasetuspto-grants-2006_08
ORD IDord-b23a0f8e590a4f68ab5573dd18023026
Source noteuspto-grants-2006_08