反应详情

温度

-5 °C

A mixture of D-lyxose (10 g, 66.6 mmol) and benzyl alcohol (50 ml) was cooled to -5° C. and hydrogen chloride was bubbled through it for 3 to 5 hours while monitoring the reaction on tlc (ethyl acetate-ethyl alcohol 7:1). To this reaction mixture diethyl ether (100 ml) was added with stirring and the mixture was allowed to stand at 5° C. for 12 hours. The crystals were filtered, washed with ether and air dried to give 4 (14.1 g, 88.1%).

1. customhydrogen chloride was bubbled through it for 3 to 5 hours
2. customthe reaction on tlc (ethyl acetate-ethyl alcohol 7:1)
3. filtrationThe crystals were filtered
4. washwashed with ether and air
5. customdried