Ethyl 4-isocyanatobenzoate → HCID 21710170, compound

HRID 964940Notes

Reaction equation

HRID 964940 reaction equation
[NH2:1][CH2:2][CH:3]1[CH2:7][CH:6]([O:8][CH3:9])[O:5][CH:4]1[O:10][CH3:11].[CH2:12]([O:14][C:15]([C:17]1[CH:22]=[CH:21][C:20]([N:23]=[C:24]=[O:25])=[CH:19][CH:18]=1)=[O:16])[CH3:13]>>[CH3:11][O:10][CH:4]1[CH:3]([CH2:2][NH:1][C:24]([NH:23][C:20]2[CH:19]=[CH:18][C:17]([C:15]([O:14][CH2:12][CH3:13])=[O:16])=[CH:22][CH:21]=2)=[O:25])[CH2:7][CH:6]([O:8][CH3:9])[O:5]1

Participants

3

Reactant 2

HCID 589805Ethyl 4-isocyanatobenzoateHCID 21710167HCID 21710167, compound

Product 1

HCID 21710170HCID 21710170, compoundYield 107.8%

Procedure

25.0 g (0.15 Mol) of 3-aminomethyl-2,5-dimethoxytetrahydrofuran and 30 g (0.15 mol) of 4-ethoxycarbonylphenyl isocyanate were reacted by method 48a. 57 g of the crude product were obtained and were reacted without purification.

Sources & evidence

ORD record
ord-e350e27250204460b831e4d8c41463f8
Source dataset
uspto-grants-1998_06
Patent number
US05773439

Reaction notes

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