HCID 178516396, compound → HCID 178516358, compound

Participants

Reaction Steps

Preparation 3: Preparation of 4-hydroxy-7-phenethylquinoline trans-4-Hydroxy-7-styrylquinoline (280 mg, 1.13 mmol) obtained in the Preparation 2 was dissolved in ethanol (200 ml), hydrogenated in the presence of 10% palladium on activated carbon (100 mg) and purified through silica gel column chromatography (Wako Gel™ C-200, methylene chloride : methanol=9 : 1) to obtain the titled compound (220mg, 78%).

Provenance & Evidence