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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 965019Generated: October 25, 2026

Ethanol → Acetic Anhydride

https://huagongshe.com/reaction/965019

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantFormaldehydeHCID 712—
Reactant4-Isopropyl-6-methoxysaccharinHCID 10147362—
ProductAcetic AnhydrideHCID 7918—
Product2-Hydroxymethyl-4-isopropyl-6-methoxysaccharinHCID 70050790—

Reaction Steps

Condensation of 4-isopropyl-6-methoxysaccharin with aqueous formaldehyde in ethanol gives 2-hydroxymethyl-4-isopropyl-6-methoxysaccharin, acetylation of which with acetic anhydride and a catalytic amount of sulfuric acid gives 2-acetoxymethyl-4-isopropyl-6-methoxysaccharin.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05773456
Source datasetuspto-grants-1998_06
ORD IDord-b9fdb1f2132f4d4a92ee1b63417e3b8d
Source noteuspto-grants-1998_06