HCID 68797768, compound → 174230-05-8

HRID 965020Notes

Reaction equation

HRID 965020 reaction equation
[ClH:1].[CH2:2]([O:4][C:5](=[O:30])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[C:13]2[C:18]([O:19][C:20]3[C:25]=1[CH:24]=[CH:23][C:22](=[NH:26])[C:21]=3[Br:27])=[C:17]([Br:28])[C:16]([NH2:29])=[CH:15][CH:14]=2)C.Cl.C(OC(=O)C1C=CC=CC=1C1C2C(OC3C=1C=CC(=N)C=3Br)=C(Br)C(N)=CC=2)CCCCCCC.Cl.C(OC(=O)C1C=CC=CC=1C1C2C(OC3C=1C=CC(=N)C=3Br)=C(Br)C(N)=CC=2)CCC.Cl.C(OC(=O)C1C=CC=CC=1C1C2C(OC3C=1C(=N)C(N)C(CC)C=3)=CC(CC)=CC=2)CCC>>[ClH:1].[CH3:2][O:4][C:5](=[O:30])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[C:13]2[C:18]([O:19][C:20]3[C:25]=1[CH:24]=[CH:23][C:22](=[NH:26])[C:21]=3[Br:27])=[C:17]([Br:28])[C:16]([NH2:29])=[CH:15][CH:14]=2

Participants

5

Reactant 4

HCID 68797768HCID 68797768, compoundHCID 68798190HCID 68798190, compoundHCID 68799282HCID 68799282, compoundHCID 86752851HCID 86752851, compound

Product 1

HCID 9871944174230-05-8

Procedure

2-(4, 5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid ethyl ester hydrochloride; 2-(4,5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid octyl ester hydrochloride; 2-(4,5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid n-butyl ester hydrochloride; 2-(6-ethyl amino-3-ethyl imino-3H-xanthen-9-yl)-benzoic acid n-butyl ester hydrochloride; and photoactivable derivatives thereof. These derivatives are utilized in an amount to achieve appropriate intracellular levels of the derivative when irradiation of a suitable wavelength and intensity is applied to photoactivate the derivative and thereby induce cell killing.

Workup

  1. customintracellular levels of the derivative when irradiation of a suitable wavelength and intensity

Sources & evidence

ORD record
ord-5d694329dfa64fc7b15cc986a6fd0636
Source dataset
uspto-grants-1998_06
Patent number
US05773460

Reaction notes

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