Methyl iodide → 131988-12-0

HRID 965024Notes

Reaction equation

HRID 965024 reaction equation
[CH3:1][I:2].[CH2:3]([O:5][C:6]1[C:10]([C:11]2[CH:12]=[N:13][CH:14]=[CH:15][CH:16]=2)=[N:9][S:8][N:7]=1)[CH3:4]>CC(C)=O>[I-:2].[CH2:3]([O:5][C:6]1[C:10]([C:11]2[CH:12]=[N+:13]([CH3:1])[CH:14]=[CH:15][CH:16]=2)=[N:9][S:8][N:7]=1)[CH3:4]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 15180131Pyridine, 3-(4-ethoxy-1,2,5-thiadiazol-3-yl)- (9CI)

Product 1

HCID 15819042131988-12-0

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.3 ml, 5 mmol) and 3-(3-ethoxy-1,2,5-thiadiazol-4-yl)pyridine (520 mg, 2.5 mmol) in acetone (10 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.72 g (83%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.72 g (83%)

Sources & evidence

ORD record
ord-aefbc07974724c85b96940092baf4cd3
Source dataset
uspto-grants-1998_06
Patent number
US05773452

Reaction notes

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