Methyl iodide → 3-(3-(4-Methylpiperidino)-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

HRID 965084Notes

Reaction equation

HRID 965084 reaction equation
[CH3:1][I:2].[CH3:3][CH:4]1[CH2:9][CH2:8][N:7]([C:10]2[C:14]([C:15]3[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=3)=[N:13][S:12][N:11]=2)[CH2:6][CH2:5]1>CC(C)=O>[I-:2].[CH3:3][CH:4]1[CH2:5][CH2:6][N:7]([C:10]2[C:14]([C:15]3[CH:16]=[N+:17]([CH3:1])[CH:18]=[CH:19][CH:20]=3)=[N:13][S:12][N:11]=2)[CH2:8][CH2:9]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 190753173-(3-(4-Methylpiperidino)-1,2,5-thiadiazol-4-yl)pyridine

Product 1

HCID 190753753-(3-(4-Methylpiperidino)-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.5 ml, 8 mmol) and 3-(3-(4-methylpiperidino)-1,2,5-thiadiazol-4-yl)pyridine (0.8 g, 3.1 mmol) in acetone (5 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 1.14 g (92%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 1.14 g (92%)

Sources & evidence

ORD record
ord-6bd07d761d77411e96a4a302c2f37aa2
Source dataset
uspto-grants-1998_06
Patent number
US05773452

Reaction notes

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