HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 3-(3-Amino-1,2,5-oxadiazol-4-yl)-1-methylpyridinium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 4-Pyridin-3-yl-1,2,5-oxadiazol-3-amine | HCID 1415523 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 3-(3-Amino-1,2,5-oxadiazol-4-yl)-1-methylpyridinium iodide | HCID 19075322 | — |
Reaction Steps
To a solution of 3-(3-amino-1,2,5-oxadiazol-4-yl)pyridine (870 mg, 5.3 mmol) in acetone (20 ml) was added methyl iodide (990 μl, 16 mmol) and the reaction mixture was stirred overnight at room temperature. The title compound precipitated and was collected by filtration (1.1 g, 69%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05773452 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-3d7e9aaee6bf406bb8fe73591f566de4 |
| Source note | uspto-grants-1998_06 |