HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86752875, compound → HCID 57282074, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86752875 | HCID 86752875 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57282074 | HCID 57282074 | — |
Reaction Steps
(3R,9S)-Ethyl-3-(8-oxo-4-oxa-1,7-diaza-tricyclo[9.6.1.012,17 ]octadeca-11(18),12,14,16-tetraen-9-ylcarbamoyl)-6-pyridin-4-yl-hexanoate hydrochloride salt was stirred in CH2Cl2 /saturated Na2 CO3 for 10 minutes. The organic layer was separated, dried, and evaporated. The crude product was crystallized from CH2Cl2 /hexanes to give (3R,9S)-ethyl-3-(8-oxo-4-oxa-1,7-diaza-tricyclo[9.6.1.012,17 ]octadeca-11(18),12,14,16-tetraen-9-ylcarbamoyl)-6-pyridin-4-yl-hexanoate, melting point 203°-205° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05773428 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-95bfa227a19b448e8aff67a1733750f8 |
| Source note | uspto-grants-1998_06 |