Acetone → {2-Isobutyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

HRID 9652Notes

Reaction equation

HRID 9652 reaction equation
[Br-].C[O:3][C:4]([C:6]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][CH:12]=2)[O:8][C:7]=1[CH2:21][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)=O.[CH3:41][C:42](=O)[CH3:43]>>[CH2:21]([C:7]1[O:8][C:9]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:18])([F:19])[F:20])=[CH:13][CH:12]=2)=[CH:10][C:6]=1[CH2:4][OH:3])[CH:42]([CH3:43])[CH3:41]

Participants

3

Reactant 2

HCID 180AcetoneHCID 86593915({3-(Methoxycarbonyl)-5-[4-(trifluoromethyl)phenyl]-2-furyl}methyl)(triphenyl)phosphonium bromide

Product 1

HCID 21986520{2-Isobutyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

Procedure

Prepared from intermediate 62 and propanone

Sources & evidence

ORD record
ord-eac842baaa6b4a0a9a150ca3464ed4ce
Source dataset
uspto-grants-2006_08
Patent number
US07091237B2

Reaction notes

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