4-Hydroxy-3,5-bis(isopropyl)benzaldehyde → (E)-3-(3,5-diisopropyl-4-hydroxyphenyl)-2-[(3-phenyl-n-propyl)aminosulfonyl]acrylonitrile

HRID 965256Notes

Reaction equation

HRID 965256 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:13]([CH3:15])[CH3:14])[C:11]=1[OH:12])[CH:7]=O)([CH3:3])[CH3:2].[C:16]1([CH2:22][CH2:23][CH2:24][NH:25][S:26]([CH2:29][C:30]#[N:31])(=[O:28])=[O:27])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH:1]([C:4]1[CH:5]=[C:6](/[CH:7]=[C:29](/[S:26]([NH:25][CH2:24][CH2:23][CH2:22][C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)(=[O:28])=[O:27])\[C:30]#[N:31])[CH:9]=[C:10]([CH:13]([CH3:15])[CH3:14])[C:11]=1[OH:12])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 827124-Hydroxy-3,5-bis(isopropyl)benzaldehydeHCID 15410494(3-Phenyl-n-propyl)aminosulfonylacetonitrile

Product 1

HCID 18185630(E)-3-(3,5-diisopropyl-4-hydroxyphenyl)-2-[(3-phenyl-n-propyl)aminosulfonyl]acrylonitrile

Procedure

M44 was prepared with 3,5-diisopropyl-4-hydroxybenzaldehyde and N-3-phenyl-n-propyl cyanomethylsulfonamide under similar conditions as described for M40.

Sources & evidence

ORD record
ord-328c3787ba02476899fefa9e5ad69093
Source dataset
uspto-grants-1998_06
Patent number
US05773476

Reaction notes

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