2-(2-Chloroethoxy)tetrahydro-2H-pyran → 1-(2-Hydroxyethyl)-3-methyl-3-methylthio-1,3-dihydro-2H-indol-2-one

HRID 965285Notes

Reaction equation

HRID 965285 reaction equation
[CH3:1][C:2]1([S:12][CH3:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[NH:4][C:3]1=[O:11].Cl[CH2:15][CH2:16][O:17]C1CCCCO1>>[OH:17][CH2:16][CH2:15][N:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[C:2]([CH3:1])([S:12][CH3:13])[C:3]1=[O:11]

Participants

3

Reactant 2

HCID 2549512-(2-Chloroethoxy)tetrahydro-2H-pyranHCID 3266193-methyl-3-methylthio-1,3-dihydro-2H-indol-2-one

Product 1

HCID 158173761-(2-Hydroxyethyl)-3-methyl-3-methylthio-1,3-dihydro-2H-indol-2-one

Procedure

Prepared from 3-methyl-3-methylthio-1,3-dihydro-2H-indol-2-one and 2-(2-chloroethoxy)tetrahydro-2H-pyran as described in Example 1.

Sources & evidence

ORD record
ord-07ac951344764f1f8c314e2d5753002b
Source dataset
uspto-grants-1998_06
Patent number
US05773448

Reaction notes

Loading…