2-(2-Chloroethoxy)tetrahydro-2H-pyran → 3-Benzyl-1-(2-hydrox-1-ethyl)-3-methylindol-2(3H)-one

HRID 965289Notes

Reaction equation

HRID 965289 reaction equation
[CH2:1]([C:8]1([CH3:18])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[NH:10][C:9]1=[O:17])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:20][CH2:21][O:22]C1CCCCO1>>[CH2:1]([C:8]1([CH3:18])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[N:10]([CH2:20][CH2:21][OH:22])[C:9]1=[O:17])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 2549512-(2-Chloroethoxy)tetrahydro-2H-pyranHCID 190750293-methyl-3-phenylmethyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 190749983-Benzyl-1-(2-hydrox-1-ethyl)-3-methylindol-2(3H)-one

Procedure

Prepared from 3-benzyl-3-methylindol-2(3H)-one and 2-(2-chloroethoxy)tetrahydro-2H-pyran.

Sources & evidence

ORD record
ord-d88e2e612ba54b59a1fbeecc770e9b18
Source dataset
uspto-grants-1998_06
Patent number
US05773448

Reaction notes

Loading…