2-(2-Chloroethoxy)tetrahydro-2H-pyran → 1-(2-Hydroxyethyl)-3-(l-methylethyl)-3-methylthio-1,3-dihydro-2H-indol-2-one

HRID 965292Notes

Reaction equation

HRID 965292 reaction equation
[CH3:1][CH:2]([C:4]1([S:14][CH3:15])[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[NH:6][C:5]1=[O:13])[CH3:3].Cl[CH2:17][CH2:18][O:19]C1CCCCO1>>[OH:19][CH2:18][CH2:17][N:6]1[C:7]2[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:4]([CH:2]([CH3:1])[CH3:3])([S:14][CH3:15])[C:5]1=[O:13]

Participants

3

Reactant 2

HCID 2549512-(2-Chloroethoxy)tetrahydro-2H-pyranHCID 190750013-(1-Methylethyl)-3-methylthio-1,3-dihydro-2H-indol-2-one

Product 1

HCID 190750201-(2-Hydroxyethyl)-3-(l-methylethyl)-3-methylthio-1,3-dihydro-2H-indol-2-one

Procedure

Prepared from 3-(1-methylethyl)-3-methylthio-1,3-dihydro-2H-indol-2-one and 2-(2-chloroethoxy)tetrahydro-2H-pyran.

Sources & evidence

ORD record
ord-9fb6f179afb348b29f74549fec0b6089
Source dataset
uspto-grants-1998_06
Patent number
US05773448

Reaction notes

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