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HRID965571

反应详情

EQUATION

反应方程式

HRID 965571 的结构方程式

REACTANTS

反应物

3
结构：ClCCl
HCID6344

Dichloromethane

CH2Cl2

结构：COc1cc([N+](=O)[O-])ccc1S(=O)(=O)Cl
HCID309458

2-Methoxy-4-nitrobenzenesulfonyl chloride

C7H6ClNO5S

结构：CNC1(CC2CCCCC2)C(=O)Nc2ccc(Cl)cc21
HCID19076572

未命名化合物

PRODUCTS

生成物

1
结构：CNC1(CC2CCCCC2)C(=O)N(S(=O)(=O)c2ccc([N+](=O)[O-])cc2OC)c2ccc(Cl)cc21
HCID19076466

未命名化合物

收率 58%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O.ClCCl
溶剂HCID21226138

未命名化合物

PROCEDURE

实验过程

This compound is prepared according to the procedure described in EXAMPLE 16 from 1.49 g of 5-chloro-3-(cyclohexylmethyl)-1,3-dihydro-3-(methylamino)indol-2-one and 1.8 g of 2-methoxy-4-nitrobenzenesulfonyl chloride. Chromatography on silica using DCM and then a DCM/AcOEt mixture (95/5; v/v) as the eluent gives 1.5 g of the expected product after crystallization from AcOEt. M.p.=207° C.

WORKUP

后处理

  1. customThis compound is prepared