HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl 4-chlorosulfonyl-3-methoxybenzoate → Benzyl 4-[[5-chloro-3-(2-chlorophenyl)-2,3-dihydro-3-(methylamino)-2-oxoindol-1-yl]sulfonyl]-3-methoxybenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl 4-chlorosulfonyl-3-methoxybenzoate | HCID 15231551 | — |
| Reactant | 5-Chloro-3-(2-chlorophenyl)-1,3-dihydro-3-(methylamino)indol-2-one | HCID 19076510 | — |
| Product | Benzyl 4-[[5-chloro-3-(2-chlorophenyl)-2,3-dihydro-3-(methylamino)-2-oxoindol-1-yl]sulfonyl]-3-methoxybenzoate | HCID 19076416 | 86.2% |
Reaction Steps
This compound is prepared according to the procedure described in step A of EXAMPLE 28 from 6 g of 5-chloro-3-(2-chlorophenyl)-1,3-dihydro-3-(methylamino)-indol-2-one and 6.66 g of benzyl 4-chlorosulfonyl-3-methoxybenzoate. 10.3 g of the expected product are obtained after crystallization from iso ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05773612 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-831a0e4785a349b8985377af8b831518 |
| Source note | uspto-grants-1998_06 |