Acetone → [1-(3,5-Dichloro-benzyl)-1H-imidazol-2-ylmethyl]-(3-fluoro-benzyl)-isopropyl-amine
Reaction equation
[C:29]([BH3-:30])#[N:31].[CH3:25][C:26]([CH3:27])=[O:28].[CH3:34][OH:35].[Cl:1][c:2]1[cH:3][c:4]([CH2:5][n:6]2[c:7]([CH2:11][NH:12][CH2:13][c:14]3[cH:15][c:16]([F:20])[cH:17][cH:18][cH:19]3)[n:8][cH:9][cH:10]2)[cH:21][c:22]([Cl:24])[cH:23]1.[Na+:32].[OH2:33]>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][n:6]2[c:7]([CH2:11][N:12]([CH2:13][c:14]3[cH:15][c:16]([F:20])[cH:17][cH:18][cH:19]3)[CH:26]([CH3:25])[CH3:27])[n:8][cH:9][cH:10]2)[cH:21][c:22]([Cl:24])[cH:23]1Participants
7
Sources & evidence
- ORD record
- ord-b2507d7cab41482783150ce4c827fc19
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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