反应详情

A mixture of ethyl 2-benzyl-3-oxobutanoate (6 g, 27.2 mmol), guanidine carbonate (2.94 g, 16.3 mmol) and ethanol (20 ml) was refluxed for 10 hours. After cooling, the precipitate was filtered and washed with water, ethanol and ether in order, to the object compound (3.62 g, 61.7%).

1. temperaturewas refluxed for 10 hours
2. temperatureAfter cooling
3. filtrationthe precipitate was filtered
4. washwashed with water, ethanol and ether in order, to the object compound (3.62 g, 61.7%)