Nitric Acid → 3,4-Dimethoxy-2-hydroxy-5-nitrobenzaldehyde

Participants

Reaction Steps

To a solution of 3,4-dimethoxy-2-hydroxybenzaldehyde (0.5 g) in acetic acid (10 ml) was added fuming nitric acid (0.12 ml). The reaction mixture was poured into ice water, the product extracted into ethyl acetate, washed with water, dried and evaporated. The product was triturated with water and filtered. Yield: 0.15 g.

Provenance & Evidence