2-Methylpyridine 1-oxide → HCID 69592043, compound

HRID 965867Notes

Reaction equation

HRID 965867 reaction equation
[N+:1]1([O-:8])[C:2]([CH3:7])=[CH:3][CH:4]=[CH:5][CH:6]=1.C([O-])(C)(C)C.[K+].[F:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=1)[CH:19]=O>>[F:15][C:16]1[CH:17]=[C:18]([CH:19]=[CH:7][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N+:1]=2[O-:8])[CH:21]=[CH:22][CH:23]=1

Participants

4

Reactant 3

HCID 136022-Methylpyridine 1-oxideHCID 680093-FluorobenzaldehydeHCID 23665647Potassium tert-butoxide

Product 1

HCID 69592043HCID 69592043, compound

Procedure

Following, the general method described in example 2a, 2-picoline-1-oxide was reacted with potassium tert.-butanolate and 3-fluoro-benzaldehyde. After extraction and chromatography the title compound was obtained as a yellow solid material. MS: m/e=215 (M+).

Workup

  1. extractionAfter extraction and chromatography the title compound
  2. customwas obtained as a yellow solid material

Sources & evidence

ORD record
ord-1e3b851147914019a74abe3db77db120
Source dataset
uspto-grants-2005_10
Patent number
US06951875B2

Reaction notes

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