Ethyl chloroformate → HCID 69992103, compound

Participants

Reaction Steps

A solution of 2-(3,4-dihydro-naphthalen-2-yl)-pyridin-4-yl-amine (0.80 g, 3.6 mmol) in pyridine (20 ml) was cooled to 0° C. and ethylchloroformate (0.47 g, 4.3 mmol) was slowly added. Stirring was continued for 72 hr. Then the solvent was evaporated and the residue was partitioned (AcOEt /H2O). The organic phase was dried (MgSO4), concentrated and chromatographed (SiO2 with CH2Cl2/CH3OH=98/2) to give the title compound (0.36 g, 36%) as a yellow oil. MS: m/e=294 (M+).

Provenance & Evidence