HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → N-[2-(1-oxiranylethoxy)phenyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | N-{2-[(1-Methyl-2-propenyl)oxy]phenyl}acetamide | HCID 22313621 | — |
| Product | N-[2-(1-oxiranylethoxy)phenyl]acetamide | HCID 22313695 | — |
Reaction Steps
The compound was prepared from N-{2-[(1-Methyl-2-propenyl)oxy]phenyl}acetamide (549 mg, 2.67 mmol) and m-chloroperbenzoic acid (80%, 923 mg, 4.28 mmol) analogously to that described in Example 8 (ii). Purification was done on silica gel with petroleum ether/ethyl acetate 10/15 as eluent. This gave separation of the two diastereomeric pairs.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06951874B2 |
| Source dataset | uspto-grants-2005_10 |
| ORD ID | ord-76ac4fe750434ad5b758261026c40c10 |
| Source note | uspto-grants-2005_10 |