Methanol → Benzoate

Participants

Reaction Steps

5 g of 1-(3,4-dihydroxy-2-methoxyphenyl)-2-(1-methylcyclopentylamino)ethanone hydrochloride is hydrogenated with 0.2 g of platinum(IV) oxide in 200 mL methanol. The catalyst is suction filtered and the solvent is distilled off under reduced pressure. The residue remaining is dissolved in ethanol and combined with 5 g of sodium benzoate. The title compound is isolated in the form of its benzoate. Yield: 4.5 g (70.5%; benzoate); melting point: 179° C.-180° C.

Provenance & Evidence