HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → 2-Methyl-1-(2,4,6-trimethylphenyl)propan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Magnesium | HCID 5462224 | — |
| Reactant | Methyl 2,4,6-trimethylbenzeneacetate | HCID 13524810 | — |
| Product | 2-Methyl-1-(2,4,6-trimethylphenyl)propan-2-ol | HCID 22314548 | 79% |
Reaction Steps
97 g (79%) of the title compound is prepared from 38 g of magnesium and 222 g of methyl iodide in 1.2 L of diethyl ether and 116 g of methyl (2,4,6-trimethylphenyl)acetate under standard conditions in a Grignard reaction. bp15: 140° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06951888B2 |
| Source dataset | uspto-grants-2005_10 |
| ORD ID | ord-f09eb783a8ef4b3d81fd1e1a96f1e762 |
| Source note | uspto-grants-2005_10 |