2,6-Di-tert-butyl-4-methoxyphenol → HCID 178506939, compound

HRID 966139Notes

Reaction equation

HRID 966139 reaction equation
[C:1]([C:5]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[C:7]([C:13]([CH3:16])([CH3:15])[CH3:14])[C:6]=1[OH:17])([CH3:4])([CH3:3])[CH3:2].C([Li:22])CCC>C1(C)C=CC=CC=1>[C:13]([C:7]1[CH:8]=[C:9]([O:11][CH3:12])[CH:10]=[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[C:6]=1[O:17][Li:22])([CH3:16])([CH3:15])[CH3:14]

Participants

4

Reactant 2

HCID 102692,6-Di-tert-butyl-4-methoxyphenolHCID 178418339Butyllithium

Product 1

HCID 178506939HCID 178506939, compoundYield 95%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Both 10 mmol (2.2 g) of monocyclopentadienyl titanium chloride(CpTiCl3) and 100 ml of toluene were added to a 200 ml Schlenk reactor in the atmosphere of inert gas. Then, 10 mmol of 2,6-di-t-butyl 4-methoxy phenoxy lithium, so obtained from the reaction between 2,6-di-t-butyl 4-methoxy phenol and n-butyl lithium, was slowly added to the mixture. The reactional solution was stirred at room temperature and stood for 1 hour. After 1 hour, some mixture was collected and was analyzed by 1H-NMR spectroscopy to ascertain the reaction results.

Sources & evidence

ORD record
ord-4da7bed3f8f745faaf6f264c543ba6ff
Source dataset
uspto-grants-2005_10
Patent number
US06951906B1

Reaction notes

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