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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 966176Generated: October 29, 2026

1-Acetylpiperazine → 1-(4-(4-[3-(4-Bromo-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl)-piperazin-1-yl)-ethanone

https://huagongshe.com/reaction/966176

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-AcetylpiperazineHCID 83795—
ReactantHCID 22313931HCID 22313931—
Product1-(4-(4-[3-(4-Bromo-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl)-piperazin-1-yl)-ethanoneHCID 22314086—

Reaction Steps

In analogy to example 3.1, 6-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-benzo[d]isothiazole and 1-Acetylpiperazine were converted to yield 1-(4-(4-[3-(4-Bromo-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl)-piperazin-1-yl)-ethanone as white solid, MS: 488(MH+, 1Br).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06951879B2
Source datasetuspto-grants-2005_10
ORD IDord-59f0a627e56d4e2f8d37ff764614584e
Source noteuspto-grants-2005_10