HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-Methoxyethyl)ethylamine → Ethyl-{4-[3-(4-fluoro-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl}-(2-methoxy-ethyl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-Methoxyethyl)ethylamine | HCID 546877 | — |
| Reactant | 6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[d]isothiazole | HCID 22314175 | — |
| Product | Ethyl-{4-[3-(4-fluoro-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl}-(2-methoxy-ethyl)-amine | HCID 22314136 | — |
Reaction Steps
In analogy to example 3.1, 6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[d]isothiazole and N-(2-Methoxyethyl)ethylamine were converted to yield Ethyl-{4-[3-(4-fluoro-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl}-(2-methoxy-ethyl)-amine which was transferred into its salt by treatment with formic acid, MS: 403 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06951879B2 |
| Source dataset | uspto-grants-2005_10 |
| ORD ID | ord-930329f5ed024042896e4a4e825bc8dc |
| Source note | uspto-grants-2005_10 |