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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 966276Generated: November 1, 2026

2-(Ethylamino)ethanol → 2-(Ethyl-{3-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-propyl}-amino)-ethanol

https://huagongshe.com/reaction/966276

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Ethylamino)ethanolHCID 8072—
ReactantMethanesulfonic acid 3-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-propyl esterHCID 86585423—
Product2-(Ethyl-{3-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-propyl}-amino)-ethanolHCID 22314071—

Reaction Steps

In analogy to example 17.1; Methanesulfonic acid 3-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-propyl ester and 2-ethylaminoethanol were converted to yield 2-(Ethyl-{3-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-propyl}-amino)-ethanol as light brown oil, MS: 409 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06951879B2
Source datasetuspto-grants-2005_10
ORD IDord-ee016e5da69c48e2be2c4d3d90f522d2
Source noteuspto-grants-2005_10