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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 966285Generated: October 31, 2026

Diethanolamine → 2-[{4-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol

https://huagongshe.com/reaction/966285

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethanolamineHCID 8113—
ReactantMethanesulfonic acid 4-[3-(4-chloro-phenyl)-benzo[d]isothiazol-6-yl]-butyl esterHCID 57428084—
Product2-[{4-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-butyl}-(2-hydroxy-ethyl)-amino]-ethanolHCID 22313963—

Reaction Steps

According to the method in example 23, Methanesulfonic acid 4-[3-(4-chloro-phenyl)-benzo[d]isothiazol-6-yl]-butyl ester and Diethanolamin were converted to yield 2-[{4-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol, MS: 405 (MH+, 1Cl).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06951879B2
Source datasetuspto-grants-2005_10
ORD IDord-d9070aea9fa14da498d83f07ae61b694
Source noteuspto-grants-2005_10