Diethanolamine → 2-[{4-[3-(4-Bromo-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol

Participants

Role	Name	HCID	Charge
Reactant	Diethanolamine	HCID 8113	—
Reactant	6-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-benzo[b]thiophene	HCID 22314056	—
Product	2-[{4-[3-(4-Bromo-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol	HCID 22314130	—

Reaction Steps

According to the method in example 29, 6-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-benzo[b]thiophene and diethanolamine were converted to yield 2-[{4-[3-(4-Bromo-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol as light yellow oil, MS: 464 (MH+,1 Br).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06951879B2
Source dataset	uspto-grants-2005_10
ORD ID	ord-ac576f58e4514be18bef76d652879f67
Source note	uspto-grants-2005_10