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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 966311Generated: November 3, 2026

Pyrrolidine → 3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl-pyrrolidine

https://huagongshe.com/reaction/966311

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiopheneHCID 22314034—
Product3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl-pyrrolidineHCID 22314006—

Reaction Steps

In analogy to example 3.1, 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and pyrrolidine were converted to yield 1-{3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl-pyrrolidine as colorless oil, MS: 356 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06951879B2
Source datasetuspto-grants-2005_10
ORD IDord-a6d0418c11824a95bfe31c704e6dbafc
Source noteuspto-grants-2005_10