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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 966313Generated: October 30, 2026

2-(Methylamino)ethanol → 2-({4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-methyl-amino)-ethanol

https://huagongshe.com/reaction/966313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Methylamino)ethanolHCID 8016—
Reactant6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[b]thiopheneHCID 22313938—
Product2-({4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-methyl-amino)-ethanolHCID 22314144—

Reaction Steps

In analogy to example 3.1, 6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and 2-(methylamino)ethanol were converted to yield 2-({4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-methyl-amino)-ethanol as colorless oil, MS: 374 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06951879B2
Source datasetuspto-grants-2005_10
ORD IDord-526fbe77c7164b788ebf6ca035053810
Source noteuspto-grants-2005_10