HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[(1,1-Dimethyl-prop-2-ynyl)-ethyl-amino]-ethanol → 2-((1,1-Dimethyl-3-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-ynyl)-ethyl-amino)-ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[(1,1-Dimethyl-prop-2-ynyl)-ethyl-amino]-ethanol | HCID 22313977 | — |
| Reactant | Trifluoro-methanesulfonic acid 3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl ester | HCID 57428077 | — |
| Product | 2-((1,1-Dimethyl-3-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-ynyl)-ethyl-amino)-ethanol | HCID 10137670 | — |
Reaction Steps
In analogy to example 14.1, Trifluoro-methanesulfonic acid 3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl ester and 2-[(1,1-Dimethyl-prop-2-ynyl)-ethyl-amino]-ethanol were converted to yield 2-((1,1-Dimethyl-3-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-ynyl)-ethyl-amino)-ethanol as off-white foam, MS: 433 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06951879B2 |
| Source dataset | uspto-grants-2005_10 |
| ORD ID | ord-accf1944805043d6ab73b731b4a08a8b |
| Source note | uspto-grants-2005_10 |