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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 966348Generated: October 30, 2026

(1,1-Dimethyl-prop-2-ynyl)-(2-methoxy-ethyl)-methyl-amine → {1,1-Dimethyl-3-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-ynyl}-(2-methoxy-ethyl)-methyl-amine

https://huagongshe.com/reaction/966348

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1-Dimethyl-prop-2-ynyl)-(2-methoxy-ethyl)-methyl-amineHCID 22314051—
ReactantTrifluoro-methanesulfonic acid 3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl esterHCID 57428077—
Product{1,1-Dimethyl-3-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-ynyl}-(2-methoxy-ethyl)-methyl-amineHCID 69289587—

Reaction Steps

In analogy to example 14.1, Trifluoro-methanesulfonic acid 3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl ester and (1,1-Dimethyl-prop-2-ynyl)-(2-methoxy-ethyl)-methyl-amine were converted to yield {1,1-Dimethyl-3-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-ynyl-(2-methoxy-ethyl)-methyl-amine as brown oil, MS: 433 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06951879B2
Source datasetuspto-grants-2005_10
ORD IDord-4c57db1daf2e4997ad0efa26b8ac6d74
Source noteuspto-grants-2005_10