HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Ethyl(1-ethynylcyclohexyl)amino)ethan-1-ol → 2-(Ethyl-{1-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-ylethynyl]-cyclohexyl}-amino)-ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Ethyl(1-ethynylcyclohexyl)amino)ethan-1-ol | HCID 22314189 | — |
| Reactant | Trifluoro-methanesulfonic acid 3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl ester | HCID 57428077 | — |
| Product | 2-(Ethyl-{1-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-ylethynyl]-cyclohexyl}-amino)-ethanol | HCID 22313983 | — |
Reaction Steps
In analogy to example 14.1, Trifluoro-methanesulfonic acid 3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl ester and 2-[Ethyl-(1-ethynyl-cyclohexyl)-amino]-ethanol were converted to yield 2-(Ethyl-{1-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-ylethynyl]-cydohexyl}-amino)-ethanol as brown oil, MS: 473.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06951879B2 |
| Source dataset | uspto-grants-2005_10 |
| ORD ID | ord-1a91471e051347d0825f8883cf3a54bd |
| Source note | uspto-grants-2005_10 |