HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 966413Generated: October 28, 2026
Thionyl Chloride → 3,5-Dichlorobenzyl chloride
https://huagongshe.com/reaction/966413
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3,5-Dichlorobenzylic alcohol | HCID 43236 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 3,5-Dichlorobenzyl chloride | HCID 137880 | 99.9% |
Reaction Steps
A solution of 12.5 g of thionyl chloride in 20 ml of chloroform is added dropwise, at RT, to a solution of 14.5 g of 3,5-dichlorobenzyl alcohol in 150 ml of chloroform, followed by heating at 40-50° C. for 8 hours and stirring at RT overnight. The mixture is concentrated under vacuum to give 16 g of the expected product, which is used without further processing.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06951940B2 |
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| Source dataset | uspto-grants-2005_10 |
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| ORD ID | ord-7060929e7eec4704a3d68e56b970c050 |
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| Source note | uspto-grants-2005_10 |
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