Trifluoroacetic acid → HCID 10132160, compound

Participants

Reaction Steps

2-Methyl-5-pyridin-3-yl-indole-1,3-dicarboxylic acid 3-benzyl ester 1-tert-butyl ester (0.027 g, 0.061 mmol, 1 eq) was suspended in dry CH2Cl2 (5 mL) under Ar. Trifluoroacetic acid (1.0 mL) was added, and the reaction mixture was stirred at room temperature. After 4 hours, the solvent was removed in vacuo, leaving 0.028 g (40% yield) of the indole-pyridine, a brown solid: LC/MS (ESI+) 343 (M+1), Anal.

Provenance & Evidence