Benzoyl chloride → HCID 131725181, compound

Participants

Reaction Steps

To a mixture of 5-(2-methanesulfonyloxy-ethyl)-2-methyl-1H-indole-3-caboxylic acid (285 mg, 0.96 mmol) and triethylamine (0.134 mL, 0.96 mmol) in dry THF (10 mL) was added benzoyl chloride (0.11 mL, 0.96 mmol). The mixture was stirred under nitrogen atmosphere at room temperature for 3 hours. The mixture was filtered and the filtrate was concentrated in vacuo to give a residue, which was triturated with diethyl ether to give 310 mg (81%) of the desired product as a off-white foam: MS(APCI−): m/z 400.0 (M−H).

Provenance & Evidence