Sodium ion → 2-Fluoro-1-(2-methoxyethoxy)-4-nitrobenzene

HRID 96677Notes

Reaction equation

HRID 96677 reaction equation
[CH3:47][O:48][CH2:49][CH2:50][OH:51].[Cl:1][c:2]1[cH:3][c:4]([NH:5][c:6]2[n:7][c:8](-[c:9]3[c:10](-[c:11]4[cH:12][c:13]([NH:14][C:15](=[O:16])[c:17]5[c:18]([F:19])[cH:20][cH:21][cH:22][c:23]5[F:24])[cH:25][cH:26][cH:27]4)[n:28][n:29]4[cH:30][cH:31][cH:32][cH:33][c:34]34)[cH:35][cH:36][n:37]2)[cH:38][cH:39][c:40]1[O:41][CH2:42][CH2:43][N:44]([CH3:45])[CH3:46].[F:54][c:55]1[cH:56][c:57]([N+:62](=[O:63])[O-:64])[cH:58][cH:59][c:60]1[F:61].[H-:52].[Na+:53]>>[CH3:47][O:48][CH2:49][CH2:50][O:51][c:60]1[c:55]([F:54])[cH:56][c:57]([N+:62](=[O:63])[O-:64])[cH:58][cH:59]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 80192-MethoxyethanolHCID 1230531,2-Difluoro-4-nitrobenzeneHCID 166653HydrideHCID 11505567N-[3-(3-{2-[(3-Chloro-4-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}pyrazolo[1,5-a]pyridin-2-yl)phenyl]-2,6-difluorobenzamide

Product 1

HCID 234980752-Fluoro-1-(2-methoxyethoxy)-4-nitrobenzene

Sources & evidence

ORD record
ord-b01b609d45d349d9a0ed4b3d6b109284
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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