8-Phenyl-1,4-dioxaspiro[4.5]decane-8-carbaldehyde → HCID 22293589, compound

Participants

Reaction Steps

Prepared from 8-phenyl-1,4-dioxaspiro[4.5]decane-8-carboxaldehyde (J. Med. Chem. 1975, 18, 593-599) and vinylmagnesium bromide according to the method of Description 22. 1H NMR (400 MHz, CDCl3) δ 1.31 (1H, br s), 1.42-1.69 (4H, m), 1.76-1.89 (2H, m), 2.23-2.28 (1H, m), 2.45-2.51 (1H, m), 3.85-3.96 (5H, m), 5.09-5.14 (2H, m), 5.55-5.63 (1H, m), and 7.21-7.39 (5H, m).

Provenance & Evidence