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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 966984Generated: October 25, 2026

4-Oxo-1-phenylcyclohexane-1-carboxylic acid → 4-Oxo-1-phenyl-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}cyclohexanecarboxamide

https://huagongshe.com/reaction/966984

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Oxo-1-phenylcyclohexane-1-carboxylic acidHCID 343886—
Reactant3,5-Bis(trifluoromethyl)benzylamineHCID 521099—
Product4-Oxo-1-phenyl-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}cyclohexanecarboxamideHCID 22293576—

Reaction Steps

Prepared from 4-oxo-1-phenylcyclohexanecarboxylic acid (Description 2) and 3,5-bis(trifluoromethyl)benzylamine according to the method of Example 177. m/z (ES+) 444 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06953792B2
Source datasetuspto-grants-2005_10
ORD IDord-7fa656b71477492699a9f1d1e2c17860
Source noteuspto-grants-2005_10