HCID 178484124, compound → HCID 178484119, compound

Participants

Reaction Steps

2.15 g (5.3 mmol) of trans-[4-(4-benzyloxy-butoxy)-cyclohexylmethyl]-methyl-carbamic acid tert-butyl ester were dissolved in 20.0 ml of methanol, 0.3 g palladium on charcoal (10%) were added and the reaction mixture hydrogenated at normal pressure until the consumption of hydrogen came to an end. Then, it was filtered over celite and evaporated giving 1.60 g (95.6%) of trans-[4-(4-hydroxy-butoxy)-cyclohexylmethyl]-methyl-carbamic acid tert-butyl ester as colorless viscous oil, MS: 315 (M+).

Provenance & Evidence