HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178484117, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Chlorophenyl chloroformate | HCID 139059 | — |
| Reactant | HCID 178484119 | HCID 178484119 | — |
| Solvent | Methanol--water (1/1) | HCID 22242641 | — |
| Product | HCID 178484117 | HCID 178484117 | — |
Reaction Steps
In analogy to the sequence described in examples 1.5 and 1.7, trans-[4-(4-hydroxy-butoxy)-cyclohexylmethyl]-methyl-carbamic acid tert-butyl ester was treated with hydrogen chloride solution in methanol/water followed by acylation with 4-chlorophenyl chloroformate giving trans-[4-(4-hydroxy-butoxy)-cyclohexylmethyl]-methyl-carbamic acid 4-chloro-phenyl ester as colorless viscous oil, MS: 370 (MH+, 1Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06953806B2 |
| Source dataset | uspto-grants-2005_10 |
| ORD ID | ord-7a14474c65c24cfd899d1fbf4c144303 |
| Source note | uspto-grants-2005_10 |