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HRID967188

反应详情

EQUATION

反应方程式

HRID 967188 的结构方程式

REACTANTS

反应物

2
结构：BrCCCCBr
HCID8056

1,4-Dibromobutane

C4H8Br2

结构：CN(C[C@H]1CC[C@H](CO)CC1)C(=O)Oc1ccc(Cl)cc1
HCID178484045

未命名化合物

PRODUCTS

生成物

1
结构：CN(C[C@H]1CC[C@H](COCCCCBr)CC1)C(=O)Oc1ccc(Cl)cc1
HCID178484052

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

3
结构：CCCC[N+](CCCC)(CCCC)CCCC.O=S(=O)([O-])O
催化剂HCID94433

未命名化合物

结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

结构：[Na+].[OH-]
溶剂HCID14798

Sodium Hydroxide

HNaO

PROCEDURE

实验过程

In analogy to the method described in example 19.1, trans-(4-hydroxymethyl-cyclohexylmethyl)-methyl-carbamic acid 4-chloro-phenyl ester (example 5.3) was reacted with 1,4-dibromo-butane in dichloromethane and aqueous sodium hydroxide solution in the presence of tetrabutylammonium hydrogensulfate to yield trans-[4-(4-bromo-butoxymethyl)-cyclohexylmethyl]-methyl-carbamic acid 4-chloro-phenyl ester as colorless solid, MS: 446 (MH+, 1Cl, 1Br).