2-(Methylamino)ethanol → HCID 178484534, compound

Participants

Reaction Steps

In analogy to the method described in example 12.1, trans-[4-(4-bromo-butoxymethyl)-cyclohexylmethyl]-methyl-carbamic acid 4-chloro-phenyl ester was reacted with (2-hydroxy-ethyl)-methyl-amine in N,N-dimethylacetamide at 50° C. for 3 hours to yield trans-(4-{4-[(2-hydroxy-ethyl)-methyl-amino]-butoxymethyl}-cyclohexylmethyl)-methyl-carbamic acid 4-chloro-phenyl ester as colorless viscous oil, MS: 441 (MH+, 1Cl).

Provenance & Evidence