HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 178484062, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 178484053 | HCID 178484053 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178484062 | HCID 178484062 | — |
Reaction Steps
In analogy to the procedure described in example 25.1, trans-N-[4-(4-bromo-(E)-but-2-enyloxymethyl)-cyclohexylmethyl]-N-methyl-4-trifluoromethyl-benzenesulfonamide (example 19.1) was reacted with imidazole in N,N-dimethylformamide in the presence of sodium hydride to yield trans-N-[4-(4-imidazol-1-yl-(E)-but-2-enyloxymethyl)-cyclohexylmethyl]-N-methyl-4-trifluoromethyl-benzenesulfonamide as yellowish solid, MS: 486 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06953806B2 |
| Source dataset | uspto-grants-2005_10 |
| ORD ID | ord-09b809069767450498e9162079aff47f |
| Source note | uspto-grants-2005_10 |