HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyanamide → 27314-97-2
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyanamide | HCID 9864 | — |
| Reactant | Benzofuroxan | HCID 68075 | — |
| Product | 27314-97-2 | HCID 135413511 | — |
Reaction Steps
More particularly, benzofuroxan is reacted with a stoichiometric excess of cyanamide in the presence of an organic base in a non-aqueous medium at about room temperature. When the reaction is complete the reaction mixture is treated with an organic acid to give tirapazamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06953852B2 |
| Source dataset | uspto-grants-2005_10 |
| ORD ID | ord-4de511242ae242cc8d37cf0bac72b8d1 |
| Source note | uspto-grants-2005_10 |