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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 967316Generated: October 25, 2026

Dansyl chloride → (4aS,8aR)-4-(3,4-Dimethoxyphenyl)-2-[1-(5-dimethylamino-naphthalene-1-sulfonyl)-piperidin-4-yl]-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one

https://huagongshe.com/reaction/967316

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDansyl chlorideHCID 11801—
Reactant(4aS,8aR)-4-(3,4-Diethoxyphenyl)-2-[1-(toluene-4-sulfonyl)-piperidin-4-yl]-4a,5,8,8a-tetrahydro-2H-phthalazin-1-oneHCID 10175016—
Product(4aS,8aR)-4-(3,4-Dimethoxyphenyl)-2-[1-(5-dimethylamino-naphthalene-1-sulfonyl)-piperidin-4-yl]-4a,5,8,8a-tetrahydro-2H-phthalazin-1-oneHCID 10153262—

Reaction Steps

Prepared from dansylchloride and starting compound A1 as described for compound 1. Crystallisation from methanol. M. p. 198-200° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06953853B2
Source datasetuspto-grants-2005_10
ORD IDord-29d3c712059b4d38919b7376f2771c2f
Source noteuspto-grants-2005_10